pentobarbital will minimize the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the extent or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Females must not pick out estradiol valerate/dienogest as their contraceptive while utilizing robust CYP3A4 inducers on account of opportunity minimize in contraceptive efficacy.
If struggling to steer clear of, double present pralsetinib dose starting off on Day seven of coadministration with potent CYP3A inducer. Immediately after inducer is discontinued for a minimum of 14 days, resume past pralsetinib dose.
pentobarbital will lessen the level or influence of propafenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.
pentobarbital will minimize the level or outcome of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not encouraged; robust cytochrome P450 enzyme inducers minimize systemic exposure to roflumilast and will lessen the therapeutic efficiency
pentobarbital will lessen the extent or outcome of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will decrease the extent or impact of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.
Keep away from; coadministration with CYP3A inducers could bring about reduced plasma concentrations of elvitegravir and/or simply a concomitantly administered protease inhibitor and bring about lack of therapeutic result also to feasible resistance
pentobarbital will lessen the extent or website result of irinotecan liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will minimize the level or result of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the extent or effect of indinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lower the level or impact of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital boosts toxicity of methoxyflurane by growing metabolism. Contraindicated. Greater metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will lower the extent or influence of solifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.